Colossal Biosciences said it cloned red wolves. Is it for real?
Colossal Biosciences said it cloned red wolves. Is it for real?

If you want to capture something wolflike, it’s best to embark before dawn. So on a morning this January, with the eastern horizon still pink-hued, I drove with two young scientists into a blanket of fog. Forty miles to the west, the industrial sprawl of Houston spawned a golden glow. Tanner Broussard’s old Toyota Tacoma…

No one’s sure if synthetic mirror life will kill us all
No one’s sure if synthetic mirror life will kill us all

For four days in February 2019, some 30 synthetic biologists and ethicists hunkered down at a conference center in Northern Virginia to brainstorm high-risk, cutting-­edge, irresistibly exciting ideas that the National Science Foundation should fund. By the end of the meeting, they’d landed on a compelling contender: making “mirror” bacteria. Should they come to be,…

What’s in a name? Moderna’s “vaccine” vs. “therapy” dilemma

Is it the Department of Defense or the Department of War? The Gulf of Mexico or the Gulf of America? A vaccine—or an “individualized neoantigen treatment”? That’s the Trump-era vocabulary paradox facing Moderna, the covid-19 shot maker whose plans for next-generation mRNA vaccines against flus and emerging pathogens have been dashed by vaccine skeptics in…

Inside the stealthy startup that pitched brainless human clones
Inside the stealthy startup that pitched brainless human clones

After operating in secrecy for years, a startup company called R3 Bio, in Richmond, California, suddenly shared details about its work last week—saying it had raised money to create nonsentient monkey “organ sacks” as an alternative to animal testing. In an interview with Wired, R3 listed three investors: billionaire Tim Draper, the Singapore-based fund Immortal…

A woman’s uterus has been kept alive outside the body for the first time
A woman’s uterus has been kept alive outside the body for the first time

“Think of this as a human body,” says Javier González. In front of me is essentially a metal box on wheels. Standing at around a meter in height, it reminds me of a stainless-steel counter in a restaurant kitchen. It is covered in flexible plastic tubing—which act as veins and arteries—connecting a series of transparent…

Here’s why some people choose cryonics to store their bodies and brains after death

This week I reported on some rather unusual research that focuses on the brain of L. Stephen Coles. Coles was a gerontologist who died from pancreatic cancer in 2014. He had spent the latter part of his career specializing in human longevity. And before he died, he decided to have his brain preserved by a…

This scientist rewarmed and studied pieces of his friend’s cryopreserved brain

L. Stephen Coles’s brain sits cushioned in a vat at a storage facility in Arizona. It has been held there at a temperature of around −146 degrees °C for over a decade, largely undisturbed. That is, apart from the time, a little over a year ago, when scientists slowly lifted the brain to take photos…

Mind-altering substances are (still) falling short in clinical trials

This week I want to look at where we are with psychedelics, the mind-altering substances that have somehow made the leap from counterculture to major focus of clinical research. Compounds like psilocybin—which is found in magic mushrooms—are being explored for all sorts of health applications, including treatments for depression, PTSD, addiction, and even obesity. Over…

Peptides are everywhere. Here’s what you need to know.

MIT Technology Review Explains: Let our writers untangle the complex, messy world of technology to help you understand what’s coming next. You can read more from the series here. Want to lose weight? Get shredded? Stay mentally sharp? A wellness influencer might tell you to take peptides, the latest cure-all in the alternative medicine arsenal.…

Measles cases are rising. Other vaccine-preventable infections could be next.

There’s a measles outbreak happening close to where I live. Since the start of this year, 34 cases have been confirmed in Enfield, a northern borough of London. Most of those affected are children under the age of 11. One in five have needed hospital treatment. It’s another worrying development for an incredibly contagious and potentially…